Panacea Diagnostics

FreeFlow™ Platform

Simplicity enables adaptability, creating multiple opportunities and scalability

All FreeFlow Variants Share the Same Surface Chemistry

This means that assays developed can be quickly and efficiently moved from laboratory to Point of Care, distributed, or be adapted from POC to high throughput

ULTRA

LAB

Point of Care and Distributed Diagnostics

28 analytes have been analysed on FreeFlow™ to date with 7 more in the current pipeline for customers/partners. For more information, data, and calibrations for FreeFlow™ family please click HERE.

FreeFlow ULTRA

  • True Single Molecule Sensitivity
  • High Throughput (240 samples/hour)
  • Automated 5ul sample volume
  • Mutiplex up to 9 assays per 5ul sample

FreeFlow ULTRA+

Create portable single cell data with absolute quantification, reproducibility and total confidence. Cells which have identical genotype do not have identical phenotype. Identical cells exposed to perturbations such as a drug, do not all respond identically. There can be a high proportion of non-responding or weakly-responding cells.

All of the capabilities of the ULTRA, but with the addition of single cell selection and analysis.

  • Cell identification from primary clinical material: 4-colour fluorescence
  • Cell selection: Optical trap and relocation within microfluidic chip
  • Individual and controlled cell lysis: Mechano-Optical lysis and chemical lysis options.
  • Cell analysis: Analyse 100’s of cells for protein and nucleic acid copy number with high accuracy and precision.

Single Cell data can be quantitatively extrapolated to lysate and  or biofluids and vice versa.

 

Instrumentation-lab

FreeFlow LAB

  • Mid way between POC and ULTRA variants
  • Moderate throughput
  • Highly efficient platform for assay development

FreeFlow POC and Distributed Diagnostics

  • Fully deskilled for POC or distributed use
  • Low cost
  • Fast Readout (3 minutes)
  • Multiplexing (Currently 9-plex can be extended to 20-plex)
  • Wide Range of Sample Types (Serum, Capillary blood from fingerpick, saliva, swabs, urine)
  • Precision and Accuracy (<5% where required)
  • High Dynamic Range (fM-mM) in one cartridge
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